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The mechanism for the generation of glutathione thiosulfinate is not yet known, although it has been speculated that the initiation of GSNO decomposition may be catalyzed by copper ions through homolysis, yielding GSH and NO [73,80]
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LL320 displayed a K i value of 1.6 ± 0.3 nM, yielding a 30-fold increased inhibition compared to 16
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