Advantage II for Dogs 12 Month Supply Over 55lb Size:One Size plush synthetic fur and feature plush synthetic fur and feature polyester bolstered sides and cushioned poly cotton base for added comfort Directions for use:ADULT HORSE (1 Advantage II Dog: 12 Month Supply This once a month topical treatment for fleas and lice on dogs and puppies seven weeks and older features a new formula with insect growth regulatory (IGR) to kill all life stages of fleas and contains Imidacloprid preventing fleas on treated pets from infesting your home Kills adult fleas already on a pet within 12 hours and re infesting fleas within two hours Waterproof Fast and easy dermal application Only one application a month necessary Safe for puppies (7 weeks old) and dogs Item Specifications: Application: Apply entire contents of tube on the dog's back between the shoulder blades